Skeletal muscle metabolism during exercise in humans.

  title={Skeletal muscle metabolism during exercise in humans.},
  author={Mark Hargreaves},
  journal={Clinical and experimental pharmacology & physiology},
  volume={27 3},
1. Contracting skeletal muscle is able to use a number of intra- and extramuscular substrates to generate ATP during exercise. These include creatine phosphate (CP), muscle glycogen, blood-borne glucose, lactate and free fatty acids (FFA), derived from either adipose tissue or intramuscular triglyceride stores. 2. During high-intensity short-duration exercise, CP degradation and the breakdown of muscle glycogen to lactate are the major energy yielding pathways, although oxidative metabolism can… CONTINUE READING
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