Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise.

@article{Brook2016SkeletalMH,
  title={Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise.},
  author={Matthew S Brook and Daniel James Wilkinson and Bethan E. Phillips and Joaqu{\'i}n P{\'e}rez-Schindler and Andrew Philp and Kenneth G C Smith and P J Atherton},
  journal={Acta physiologica},
  year={2016},
  volume={216 1},
  pages={15-41}
}
Skeletal muscles comprise a substantial portion of whole body mass and are integral for locomotion and metabolic health. Increasing age is associated with declines in both muscle mass and function (e.g. strength-related performance, power) with declines in muscle function quantitatively outweighing those in muscle volume. The mechanisms behind these declines are multi-faceted involving both intrinsic age-related metabolic dysregulation and environmental influences such as nutritional and… CONTINUE READING