Skeletal muscle fibers count on nuclear numbers for growth.

@article{Prasad2021SkeletalMF,
  title={Skeletal muscle fibers count on nuclear numbers for growth.},
  author={Vikram Prasad and Douglas P. Millay},
  journal={Seminars in cell \& developmental biology},
  year={2021}
}
Skeletal muscle cells are noteworthy for their syncytial nature, with each myofiber accumulating hundreds or thousands of nuclei derived from resident muscle stem cells (MuSCs). These nuclei are accrued through cell fusion, which is controlled by the two essential fusogens Myomaker and Myomerger that are transiently expressed within the myogenic lineage. While the absolute requirement of fusion for muscle development has been known for decades, the underlying need for the magnitude of… 
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