Skeletal muscle-derived progenitor cells exhibit neural competence.

  title={Skeletal muscle-derived progenitor cells exhibit neural competence.},
  author={Takako Kondo and Jamie Case and Edward F Srour and Eri Hashino},
  volume={17 1},
Skeletal muscle contains heterogenous progenitor cells that give rise to muscle, hematopoietic cells and bone. The exact phenotypic definition of skeletal muscle progenitor cells has not been fully elucidated nor the potential of these cells to differentiate into neurons. Here, we demonstrate that phenotypically homogenous skeletal muscle progenitor cells defined as Lin-CD45-CD117-CD90+ cells express neural stem cell markers and are responsive to neural induction signals. When exposed to neural… CONTINUE READING