Skeletal muscle depletion is associated with reduced plasma (n-3) fatty acids in non-small cell lung cancer patients.

@article{Murphy2010SkeletalMD,
  title={Skeletal muscle depletion is associated with reduced plasma (n-3) fatty acids in non-small cell lung cancer patients.},
  author={Rachel A. Murphy and Marina Mourtzakis and Quincy Siu-Chung Chu and Tony J Reiman and Vera C Mazurak},
  journal={The Journal of nutrition},
  year={2010},
  volume={140 9},
  pages={
          1602-6
        }
}
Upwards of 50% of newly diagnosed advanced lung cancer patients have severe muscle wasting (sarcopenia). Supplementation with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in advanced cancer has been shown to attenuate lean tissue wasting. However, the relationship between muscle mass and plasma (n-3) fatty acids in the absence of supplementation is unclear. We aimed to determine how plasma phospholipid (n-3) fatty acids relate to sarcopenia and change in muscle mass in non-small… CONTINUE READING
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