Skeletal muscle autophagy: a new metabolic regulator

@article{Neel2013SkeletalMA,
  title={Skeletal muscle autophagy: a new metabolic regulator},
  author={Brian A. Neel and Yuxi Lin and Jeffrey E. Pessin},
  journal={Trends in Endocrinology & Metabolism},
  year={2013},
  volume={24},
  pages={635-643}
}
Autophagy classically functions as a physiological process to degrade cytoplasmic components, protein aggregates, and/or organelles, as a mechanism for nutrient breakdown, and as a regulator of cellular architecture. Proper autophagic flux is vital for both functional skeletal muscle, which controls the support and movement of the skeleton, and muscle metabolism. The role of autophagy as a metabolic regulator in muscle has been previously studied; however, the underlying molecular mechanisms… CONTINUE READING

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