Skeletal muscle aging and the mitochondrion

@article{Johnson2013SkeletalMA,
  title={Skeletal muscle aging and the mitochondrion},
  author={Matthew L. Johnson and M. Robinson and K. Nair},
  journal={Trends in Endocrinology \& Metabolism},
  year={2013},
  volume={24},
  pages={247-256}
}
Decline in human muscle mass and strength (sarcopenia) is a hallmark of the aging process. A growing body of research in the areas of bioenergetics and protein turnover has placed the mitochondria at the center of this process. It is now clear that, unless an active lifestyle is rigorously followed, skeletal muscle mitochondrial decline occurs as humans age. Increasing research on mitochondrial biology has elucidated the regulatory pathways involved in mitochondrial biogenesis, many of which… Expand
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