Skeletal modifications in mucopolysaccharidoses: an overview.

  title={Skeletal modifications in mucopolysaccharidoses: an overview.},
  author={Laura Scaramuzzo and Carlo Perisano and Angelo Leone and Calogero Graci and Maria Silvia Spinelli and Giulio Di Giacomo and Emily Venanzi and Alfredo Schiavone Panni and Giulio Maccauro},
  journal={Journal of biological regulators and homeostatic agents},
  volume={26 1},
The mucopolysaccharidoses (MPS) are a group of rare diseases characterized by deficiencies in different enzymes required for degradation of complex carbohydrates. The enzymatic deficiencies lead to lysosomal accumulation of dermatan sulphate, heparan sulphate, and keratan sulphate in different tissue resulting in multi-system complications. Six different… CONTINUE READING