Skeletal malformations associated with esophageal atresia: clinical and experimental studies.


BACKGROUND/PURPOSE Patients with esophageal atresia (EA) often have skeletal malformations. The purpose of this study is to examine if similar defects occur in rat fetuses prenatally exposed to Adriamycin, a chemical capable of causing EA in these animals. METHODS The charts of 443 babies with EA were reviewed to assess the incidence and nature of these… (More)