Skeletal involvement in children who have chronic granulomatous disease.

  title={Skeletal involvement in children who have chronic granulomatous disease.},
  author={Paul D. Sponseller and Harry L Malech and Edward F. McCarthy and Steven F. Horowitz and G E Jaffe and John I. Gallin},
  journal={The Journal of bone and joint surgery. American volume},
  volume={73 1},
Chronic granulomatous disease is a rare disorder of the oxidative metabolism of the white blood cells that results in immunodeficiency. In a retrospective review of the records of forty-two patients who had chronic granulomatous disease, we identified thirteen patients who had a total of twenty skeletal infections. Two types of infection were noted: Type 1, which resulted from a direct spread of the infection from an adjacent focus, usually of fungus or mycobacteria, and Type 2, which resulted… CONTINUE READING


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