Skeletal assessment in neuroblastoma--the pitfalls of iodine-123-MIBG scans.

  title={Skeletal assessment in neuroblastoma--the pitfalls of iodine-123-MIBG scans.},
  author={Isky Gordon and A Michael Peters and Alisa Gutman and Sean E Morony and Claire Dicks-Mireaux and J. Stewart Pritchard},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={31 2},
This study was carried out to compare iodine-123 metaiodobenzylguanidine ([I123I]MIBG) and technetium-99m-methylene diphosphonate bone scans (99mTc-MDP) in the detection of skeletal involvement by neuroblastoma. Forty-four children with neuroblastoma underwent both [123I] MIBG and 99mTc-MDP scans within a 4-wk period; bone marrow examination also was performed; all these investigations were done both at diagnosis and at follow-up. At diagnosis, four children with Stage 4 disease had normal… CONTINUE READING