Skeletal actions of intermittent parathyroid hormone: effects on bone remodelling and structure.

@article{Compston2007SkeletalAO,
  title={Skeletal actions of intermittent parathyroid hormone: effects on bone remodelling and structure.},
  author={Juliet E Compston},
  journal={Bone},
  year={2007},
  volume={40 6},
  pages={1447-52}
}
Intermittent administration of parathyroid hormone peptides has anabolic skeletal effects and reduces fracture risk in postmenopausal women with osteoporosis but the cellular and structural mechanisms by which these effects are mediated have not been fully established. In cancellous and endocortical bone, there is evidence that both modelling and remodelling-based formation contribute to the increase in bone mass although the contribution of these at different time points in the response to PTH… CONTINUE READING
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