Skeletal Muscle Regeneration, Repair and Remodelling in Aging: The Importance of Muscle Stem Cells and Vascularization.

@article{Joanisse2017SkeletalMR,
  title={Skeletal Muscle Regeneration, Repair and Remodelling in Aging: The Importance of Muscle Stem Cells and Vascularization.},
  author={Sophie D. Joanisse and Joshua P. Nederveen and Tim Snijders and Bryon R. McKay and Gianni Parise},
  journal={Gerontology},
  year={2017},
  volume={63 1},
  pages={
          91-100
        }
}
Sarcopenia is the age-related loss of skeletal muscle mass and strength. Ultimately, sarcopenia results in the loss of independence, which imposes a large financial burden on healthcare systems worldwide. A critical facet of sarcopenia is the diminished ability for aged muscle to regenerate, repair and remodel. Over the years, research has focused on elucidating underlying mechanisms of sarcopenia and the impaired ability of muscle to respond to stimuli with aging. Muscle-specific stem cells… CONTINUE READING