Sjögren's syndrome with acute renal failure caused by renal pseudolymphoma.

  title={Sj{\"o}gren's syndrome with acute renal failure caused by renal pseudolymphoma.},
  author={Patrice Cacoub and Claudia Ginsburg and Zoubida Mezalek Tazi and H{\'e}l{\`e}ne Beaufils and Fr{\'e}d{\'e}ric Charlotte and Fred Davi and Patrice P Carde and Pierre Godeau},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={28 5},
A 56-year-old man with Sjögren's syndrome was found to have acute renal failure. Immunopathologic analysis of renal biopsy specimens showed polyclonal lymphocytic interstitial infiltration. DNA analysis of the T-cell receptor and the heavy chain immunoglobulin genes showed a polyclonal pattern of gene rearrangements. Renal failure caused by this pseudolymphoma regressed dramatically with steroid therapy. This is the first reported case of proven renal pseudolymphoma that regressed with steroid… CONTINUE READING