Sjögren's syndrome: mechanisms of pathogenesis involve interaction of immune and neurosecretory systems.

@article{Fox2002SjgrensSM,
  title={Sj{\"o}gren's syndrome: mechanisms of pathogenesis involve interaction of immune and neurosecretory systems.},
  author={Robert Irving Fox and Michael Stern},
  journal={Scandinavian journal of rheumatology. Supplement},
  year={2002},
  volume={116},
  pages={3-13}
}
Although biopsies of salivary and lacrimal glands from patients with Sjögren's syndrome (SS) have focal lymphocytic infiltrates and partial destruction of glandular secretory units (acinar and ductal structures), the degree of dryness is beyond that expected for the level of glandular destruction. The failure to exhibit adequate secretory function is not… CONTINUE READING