Sjögren's syndrome: autoimmune epithelitis.

  title={Sj{\"o}gren's syndrome: autoimmune epithelitis.},
  author={M. N. Manoussakis and H M Moutsopoulos},
  journal={Bailliere's best practice & research. Clinical rheumatology},
  volume={14 1},
Sjögren's syndrome (SS) is a chronic autoimmune disorder of the exocrine glands of unknown aetiology, which is typically associated with focal lymphocytic infiltrates of glandular tissues and autoantibody responses against the Ro(SSA) and La(SSB) ribonucleoproteins. In almost one-third of patients disease involves various extraglandular sites, whereas approximately 5% of patients may also develop malignant B-cell lymphoma. In addition, features of SS are frequently encountered (5-20%) in… CONTINUE READING
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