Size-selective uptake of colloidal low density lipoprotein aggregates by cultured white blood cells.

@article{Walters2010SizeselectiveUO,
  title={Size-selective uptake of colloidal low density lipoprotein aggregates by cultured white blood cells.},
  author={Michael Jason Walters and Steven P. Wrenn},
  journal={Journal of colloid and interface science},
  year={2010},
  volume={350 2},
  pages={494-501}
}
This paper illustrates how principles of colloid science are useful in studying atherosclerosis. Accumulation of foam cells in the arterial intima is a key step in atherogenesis. The extent of foam cell formation is enhanced by low density lipoprotein (LDL) aggregates, and we have previously shown that the size of sphingomyelinase (Smase)-hydrolysis-induced aggregates depends directly on the concentration of ceramide generated in the LDL phospholipid monolayer, mediated by the hydrophobic… CONTINUE READING

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