Size regulation in chimaeric mouse embryos.

@article{Buehr1974SizeRI,
  title={Size regulation in chimaeric mouse embryos.},
  author={Mia Buehr and Anne McLaren},
  journal={Journal of embryology and experimental morphology},
  year={1974},
  volume={31 1},
  pages={229-34}
}
When mouse embryos at early stages are aggregated and cultured in vitro, they form a morula and, eventually, a blastocyst which is roughly proportional in size to the number of embryos which contributed to it (Tarkowski, 1961; Mintz, 1965). Cell counts have shown that blastocysts derived from two 8-cell stages contain twice the number of cells of normal blastocysts (Bowman & McLaren, unpublished observations). However, when such a blastocyst is transferred to a 'foster-mother' and allowed to… CONTINUE READING

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