Size-dependent toxicity of silica nano-particles to Chlorella kessleri.

@article{Fujiwara2008SizedependentTO,
  title={Size-dependent toxicity of silica nano-particles to Chlorella kessleri.},
  author={Kitao Fujiwara and Hitoshi Suematsu and Emiko Kiyomiya and Motohide Aoki and Mamiko Sato and Nobuko Moritoki},
  journal={Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering},
  year={2008},
  volume={43 10},
  pages={1167-73}
}
SiO(2) nano-particles were found to exhibit size-dependent toxicity toward the alga, Chlorella kessleri. Small SiO(2) nano-particles exhibit stronger toxicity: 50% inhibitory concentrations (IC(50)) value for 5 nm = 0.8 +/- 0.6%, 26 nm = 7.1 +/- 2.8%, and 78 nm = 9.1 +/- 4.7%. Enlargement of the cell body was observed by flow cytometry, which is due to the presence of structures that obstructed cell division. Optical and transmission microscopes were used to observe coagulated cells with… CONTINUE READING

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