Size-dependent genotoxicity of graphene nanoplatelets in human stem cells.

  title={Size-dependent genotoxicity of graphene nanoplatelets in human stem cells.},
  author={Omid Akhavan and Elham Ghaderi and Alireza Akhavan},
  volume={33 32},
Reduced graphene oxide nanoplatelets (rGONPs) were synthesized by sonication of covalently PEGylated GO sheets followed by a chemical reduction using hydrazine and bovine serum albumin. Human mesenchymal stem cells (hMSCs), as a fundamental factor in tissue engineering, were isolated from umbilical cord blood (as a recently proposed source for extracting fresh hMSCs) to investigate, for the first time, the size-dependent cyto- and geno-toxic effects of the rGONPs on the cells. The cell… CONTINUE READING


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