Size and structure of an epistatic space

Abstract

The evolutionary dynamics of human Influenza A virus presents a challenging theoretical problem. An extremely high mutation rate allows the virus to escape, at each epidemic season, the host immune protection elicited by previous infections. At the same time, at each given epidemic season a single quasi-species, that is a set of closely related strains, is… (More)
DOI: 10.1209/0295-5075/101/68003

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