Size and dynamics of caveolae studied using nanoparticles in living endothelial cells.

@article{Wang2009SizeAD,
  title={Size and dynamics of caveolae studied using nanoparticles in living endothelial cells.},
  author={Zhenjia Wang and Chinnaswamy Tiruppath{\`i} and Richard D Minshall and Asrar B. Malik},
  journal={ACS nano},
  year={2009},
  volume={3 12},
  pages={4110-6}
}
Caveolae are plasma membrane invaginations prominent in all endothelial cells lining blood vessels. Caveolae characteristically bud to form free cytoplasmic vesicles capable of transporting carrier proteins such as albumin through the cell. However, caveolae size distribution and dynamics in living endothelial cells and ability of caveolae to internalize nanoparticles are not well understood. We demonstrate here the design of a dual-color nanoparticle pair to measure noninvasively caveolae size… CONTINUE READING
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