Sixty years of lithium responders.

  • Paul Grof
  • Published 2010 in Neuropsychobiology


It has been 60 years since Cade first described patients who responded to antimanic lithium treatment. Two decades later, responders to lithium stabilization emerged in larger numbers. The responses of many severely ill bipolar patients to lithium were striking and called for an explanation. Remarkable reactions to a simple ion generated hope for an… (More)
DOI: 10.1159/000314305


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