Sixty-five years since the New York heat wave: advances in sweat testing for cystic fibrosis.

@article{Collie2014SixtyfiveYS,
  title={Sixty-five years since the New York heat wave: advances in sweat testing for cystic fibrosis.},
  author={Jake T B Collie and Robert J. Massie and Oliver A H Jones and Vicky A Legrys and Ronda F. Greaves},
  journal={Pediatric pulmonology},
  year={2014},
  volume={49 2},
  pages={106-17}
}
The sweat test remains important as a diagnostic test for cystic fibrosis (CF) and has contributed greatly to our understanding of CF as a disease of epithelial electrolyte transport. The standardization of the sweat test, by Gibson and Cooke [Gibson and Cooke (1959) Pediatrics 1959;23:5], followed observations of excessive dehydration amongst patients with CF and confirmed the utility as a diagnostic test. Quantitative pilocarpine iontophoresis remains the gold standard for sweat induction… CONTINUE READING
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