Six-year results of spironolactone and testolactone treatment of familial male-limited precocious puberty with addition of deslorelin after central puberty onset.

@article{Leschek1999SixyearRO,
  title={Six-year results of spironolactone and testolactone treatment of familial male-limited precocious puberty with addition of deslorelin after central puberty onset.},
  author={Ellen Werber Leschek and John Vann Jones and Kevin M. Barnes and Suvimol Chirathivat Hill and Gordon B. Cutler},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 1},
  pages={175-8}
}
Short term treatment with spironolactone, testolactone, and, after the onset of central puberty, deslorelin can normalize the rate of growth and bone maturation in boys with familial male-limited precocious puberty. To test the hypothesis that this treatment can achieve long term normalization of the growth and development of these children, we examined the growth rate, bone maturation rate (change in bone age/change in chronological age), and predicted adult height of 10 boys who were treated… CONTINUE READING
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