Six weeks of continuous intravenous cyclosporine and short-course methotrexate as prophylaxis for acute graft-versus-host disease after allogeneic bone marrow transplantation.

Abstract

The feasibility and toxicity of six-week continuous intravenous 3 mg/kg/day cyclosporine (CsA) treatment in conjunction with a short course of methotrexate (MTX) was studied in 69 consecutive patients after HLA genotypically identical bone marrow transplantation. In light of the uncertain efficacy of prolonged oral CsA immunoprophylaxis in preventing de… (More)

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Cite this paper

@article{Beelen1990SixWO, title={Six weeks of continuous intravenous cyclosporine and short-course methotrexate as prophylaxis for acute graft-versus-host disease after allogeneic bone marrow transplantation.}, author={Driek Beelen and Klaus Quabeck and Bonnie N Kaiser and Johannes Wiefelsp{\"u}tz and Max Ernst Scheulen and Ullrich Graeven and Hans Grosse-Wilde and Herbert Gottfried Sayer and Ulrich Sch{\"a}fer}, journal={Transplantation}, year={1990}, volume={50 3}, pages={421-7} }