Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease.

@article{Baum2008SixmonthRP,
  title={Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease.},
  author={L. Baum and C. W. Lam and S. Cheung and T. Kwok and V. Lui and J. Tsoh and L. Lam and Vivian Yee-fong Leung and E. Hui and Chelsia Ng and J. Woo and H. Chiu and W. Goggins and B. Zee and K. F. Cheng and C. Fong and A. Wong and Hazel Mok and M. Chow and P. C. Ho and S. Ip and C. S. Ho and X. Yu and Caroline Y L Lai and M. C. Chan and S. Szeto and I. H. Chan and V. Mok},
  journal={Journal of clinical psychopharmacology},
  year={2008},
  volume={28 1},
  pages={
          110-3
        }
}
  • L. Baum, C. W. Lam, +25 authors V. Mok
  • Published 2008
  • Medicine
  • Journal of clinical psychopharmacology
  • To the Editors:Curcumin is a polyphenolic molecule that comprises approximately 5% of turmeric, giving the spice its color but not flavor. It is used in processed foods as a yellow coloring. 1 Because of its anti-inflammatory and antioxidant properties, curcumin has been tested in animal models of A 
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    References

    SHOWING 1-10 OF 27 REFERENCES
    Fixed-dose trial of the single isomer SSRI escitalopram in depressed outpatients.
    • 335
    The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse
    • 1,280
    • PDF
    Curry consumption and cognitive function in the elderly.
    • 266
    • PDF
    Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models.
    • L. Baum, A. Ng
    • Chemistry, Medicine
    • Journal of Alzheimer's disease : JAD
    • 2004
    • 345
    Escitalopram in the treatment of panic disorder: a randomized, double-blind, placebo-controlled trial.
    • 142
    Biological activities of Curcuma longa L.
    • 603
    • PDF
    Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology
    • 456
    • PDF