Six groups of the OXY beta-Lactamase evolved over millions of years in Klebsiella oxytoca.

@article{Fvre2005SixGO,
  title={Six groups of the OXY beta-Lactamase evolved over millions of years in Klebsiella oxytoca.},
  author={Cindy F{\`e}vre and Mehdi Jbel and Virginie Passet and François-Xavier Weill and Patrick Grimont and Sylvain Brisse},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 8},
  pages={3453-62}
}
The diversity and evolution of the class A OXY beta-lactamase from Klebsiella oxytoca were investigated and compared to housekeeping gene diversity. The entire bla(OXY) coding region was sequenced in 18 clinical isolates representative of the four K. oxytoca beta-lactamase gene groups bla(OXY-1) to bla(OXY-4) and of two new groups identified here, bla(OXY-5) (with four isolates with pI 7.2 and one with pI 7.7) and bla(OXY-6) (with four isolates with pI 7.75 and three with pI 8.1). Genes bla(OXY… CONTINUE READING

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