Six Innexins Contribute to Electrical Coupling of C. elegans Body-Wall Muscle

@inproceedings{Liu2013SixIC,
  title={Six Innexins Contribute to Electrical Coupling of C. elegans Body-Wall Muscle},
  author={Ping Liu and Bojun Chen and Zeynep F. Altun and Maegan J. Gross and Alan Shan and Benjamin Schuman and David H. Hall and Zhao-Wen Wang},
  booktitle={PloS one},
  year={2013}
}
C. elegans body-wall muscle cells are electrically coupled through gap junctions. Previous studies suggest that UNC-9 is an important, but not the only, innexin mediating the electrical coupling. Here we analyzed junctional current (I j ) for mutants of additional innexins to identify the remaining innexin(s) important to the coupling. The results suggest that a total of six innexins contribute to the coupling, including UNC-9, INX-1, INX-10, INX-11, INX-16, and INX-18. The I j deficiency in… CONTINUE READING
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