Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors.

Abstract

Molecular mechanisms of anesthetic action on neurotransmitter receptors are poorly understood. The major excitatory neurotransmitter in the central nervous system is glutamate, and recent studies found that volatile anesthetics inhibit the function of the alpha-amino-3-hydroxyisoxazolepropionic acid subtype of glutamate receptors (e.g. glutamate receptor 3… (More)

Topics

10 Figures and Tables

Cite this paper

@article{Minami1998SitesOV, title={Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors.}, author={Kentaro Minami and Marilee J. Wick and Yael Stern-Bach and Jo Ellen Dildy-Mayfield and Susan J. Brozowski and Edson Luck T. Gonzales and James R. Trudell and R. A. Harris}, journal={The Journal of biological chemistry}, year={1998}, volume={273 14}, pages={8248-55} }