Sites in the brain at which cholecystokinin octapeptide (CCK-8) acts to suppress feeding in rats: a mapping study.

@article{Schick1990SitesIT,
  title={Sites in the brain at which cholecystokinin octapeptide (CCK-8) acts to suppress feeding in rats: a mapping study.},
  author={Rafael Reinhold Schick and Gail J. Harty and Tony L. Yaksh and Vay Liang W. Go},
  journal={Neuropharmacology},
  year={1990},
  volume={29 2},
  pages={109-18}
}
In this study, an examination was made of the sites in the brain of the rat at which the injection of cholecystokinin octapeptide (CCK-8) would alter food intake. Rats fasted for 24 hr received intracerebral injections of CCK-8 (1 nmol) or an equal volume of saline (0.5 microliters), into various sites in the brain through permanently implanted stainless steel cannulae. After prior acclimatisation to individual plexiglass compartments, latency to feed, as well as consumption of food and water… CONTINUE READING

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