Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues.

@article{Raclot1997SitespecificRO,
  title={Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues.},
  author={Thierry Raclot and Ren{\'e} Groscolas and Dominique Langin and Pascal Ferr{\'e}},
  journal={Journal of lipid research},
  year={1997},
  volume={38 10},
  pages={1963-72}
}
Dietary n-3 polyunsaturated fatty acids (n-3 PUFAs) limit abdominal fat depot hypertrophy. This could be due to regulation of the expression of proteins involved in adipose tissue metabolism. We investigated in vivo whether fatty acid synthase (FAS), hormone-sensitive lipase (HSL), lipoprotein lipase (LPL), phosphoenolpyruvate carboxykinase (PEPCK), CCAAT/enhancer binding protein alpha (C/EBP alpha), and leptin mRNA levels are affected in retroperitoneal (RP) and subcutaneous adipose tissues… CONTINUE READING

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