Site-specific recombination of P 2-like phages ; possible tools for safe gene therapy

Abstract

Bacteriophages are viruses that infect bacteria. The temperate P2-like bacteriophages integrate their genome into the E. coli host genome by a site-specific recombination event upon lysogenization. The integrative recombination occurs between a specific sequence in the phage genome, attP, and a specific sequence in the host genome, attB, generating the… (More)

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