Site-specific rearrangements in the long terminal repeat of extra mouse mammary tumor proviruses in murine T-cell leukemias.

@article{Michalides1986SitespecificRI,
  title={Site-specific rearrangements in the long terminal repeat of extra mouse mammary tumor proviruses in murine T-cell leukemias.},
  author={Rob J.A.M Michalides and E. B. Wagenaar},
  journal={Virology},
  year={1986},
  volume={154 1},
  pages={76-84}
}
Extra MMTV proviruses in T-cell leukemias of GR and C57/BL10 mice contain alterations in their long terminal repeat (LTR) sequence. The four different leukemias studied contain different deletions, but common hallmarks were observed around the recombination sites. At the 5' end of the deletions we observed a common nonamer sequence, AGACAGGTG, in two leukemias and an almost identical sequence, AGAGCAGGTG, in two other leukemias. At the 3' end of the deletions we invariably found a common… CONTINUE READING
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