Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine.

@article{Carrithers2002SitespecificEO,
  title={Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine.},
  author={Stephen L Carrithers and Brian A. Jackson and Wei Yen Cai and Richard N. Greenberg and Cobern E. Ott},
  journal={Regulatory peptides},
  year={2002},
  volume={107 1-3},
  pages={87-95}
}
Guanylin and uroguanylin are newly discovered intestinal peptides that have been shown to affect NaCl transport in both the intestine and kidney. The present study tests the hypothesis that guanylin and uroguanylin mRNA expression in each major region of the intestine is regulated by NaCl intake. Semiquantitative multiplex RT-PCR analysis was used to determine the molecular expression of guanylin and uroguanylin in the duodenum, jejunum, ileum, and colon in rats maintained on low (LS), normal… CONTINUE READING