Site-specific cleavage of natural mRNA sequences by newly designed hairpin catalytic RNAs.

Abstract

The negative strand of tobacco ringspot virus satellite RNA is a self-cleaving RNA. Its catalytic domain and substrate domain have been identified, and the catalytic domain has been named hairpin catalytic RNA. Here we report the construction of a plasmid containing a modified hairpin catalytic RNA sequence that can be transcribed in vitro. Because this… (More)

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Cite this paper

@article{Kikuchi1991SitespecificCO, title={Site-specific cleavage of natural mRNA sequences by newly designed hairpin catalytic RNAs.}, author={Yuichi Kikuchi and Nobuo Sasaki}, journal={Nucleic acids research}, year={1991}, volume={19 24}, pages={6751-5} }