Site-independent prognostic value of chromosome 9q loss in primary gastrointestinal stromal tumours.

@article{Gunawan2004SiteindependentPV,
  title={Site-independent prognostic value of chromosome 9q loss in primary gastrointestinal stromal tumours.},
  author={Bastian Gunawan and Hans-Juergen Schulten and Anja von Heydebreck and Bettina Schmidt and Christina Enders and J{\"o}rg H{\"o}er and Claus Oliver Langer and Phillip Sch{\"u}ler and Christian G Schindler and Jens Kuhlgatz and L{\'a}szl{\'o} F{\"u}zesi},
  journal={The Journal of pathology},
  year={2004},
  volume={202 4},
  pages={
          421-9
        }
}
Although the significance of tumour site for estimating malignant potential in gastrointestinal stromal tumours (GISTs) has recently been recognized, site-specific genetic patterns have not to date been defined. This study examined 52 c-kit-positive primary GISTs (with a mean follow-up of 42.3 months in 51 cases) from three different locations (35 gastric, 12 small intestinal, and five colorectal) using comparative genomic hybridization (CGH). In general, tumour site correlated with key… CONTINUE READING
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