Site-heterogeneous mutation-selection models within the PhyloBayes-MPI package

@inproceedings{Rodrigue2014SiteheterogeneousMM,
  title={Site-heterogeneous mutation-selection models within the PhyloBayes-MPI package},
  author={Nicolas Rodrigue and Nicolas Lartillot},
  booktitle={Bioinformatics},
  year={2014}
}
MOTIVATION In recent years, there has been an increasing interest in the potential of codon substitution models for a variety of applications. However, the computational demands of these models have sometimes lead to the adoption of oversimplified assumptions, questionable statistical methods or a limited focus on small data sets. RESULTS Here, we offer a scalable, message-passing-interface-based Bayesian implementation of site-heterogeneous codon models in the mutation-selection framework… CONTINUE READING
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