Site-directed mutations in the potyvirus HC-Pro gene affect helper component activity, virus accumulation, and symptom expression in infected tobacco plants.

@article{Atreya1992SitedirectedMI,
  title={Site-directed mutations in the potyvirus HC-Pro gene affect helper component activity, virus accumulation, and symptom expression in infected tobacco plants.},
  author={C. D. Atreya and P. L. Atreya and David Thornbury and Thomas P. Pirone},
  journal={Virology},
  year={1992},
  volume={191 1},
  pages={106-11}
}
Helper component (HC-Pro) is a virus-encoded nonstructural protein required for aphid transmission of potyviruses. In the tobacco vein mottling virus (TVMV) polyprotein, HC-Pro represents a 457 residue polypeptide from amino acid position 257 to 713. Previous sequence comparison studies have suggested that mutations of one or two specific amino acid… CONTINUE READING