Site-Specific Mobilization of Vinyl Chloride Respiration Islands by a Mechanism Common in Dehalococcoides

@inproceedings{McMurdie2011SiteSpecificMO,
  title={Site-Specific Mobilization of Vinyl Chloride Respiration Islands by a Mechanism Common in Dehalococcoides},
  author={Paul J. McMurdie and Laura A. Hug and Elizabeth A. Edwards and Susan P. Holmes and Alfred M Spormann},
  booktitle={BMC Genomics},
  year={2011}
}
Vinyl chloride is a widespread groundwater pollutant and Group 1 carcinogen. A previous comparative genomic analysis revealed that the vinyl chloride reductase operon, vcrABC, of Dehalococcoides sp. strain VS is embedded in a horizontally-acquired genomic island that integrated at the single-copy tmRNA gene, ssrA. We targeted conserved positions in available genomic islands to amplify and sequence four additional vcrABC -containing genomic islands from previously-unsequenced vinyl chloride… CONTINUE READING