Sitagliptin can inhibit the development of hepatic steatosis in high-fructose diet-fed ob/ob mice

Abstract

The beneficial effect of dipeptidyl peptidase-4 inhibition on diet-induced extra-pancreatic effects, especially on liver tissue remains poorly understood. Thus, we made the experimental designs as follows; five-week-old male ob/ob mice, which develop type 2 diabetic mellitus and nonalcoholic fatty liver disease by taking a high-carbohydrate diet (HCD), were… (More)
DOI: 10.3164/jcbn.15-84

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