Sister chromatid exchange analysis in the lymphocytes of patients with ankylosing spondylitis.

@article{Snmez1997SisterCE,
  title={Sister chromatid exchange analysis in the lymphocytes of patients with ankylosing spondylitis.},
  author={Seyhan S{\"o}nmez and Kazım Şenel and Sitki Oztaş and A Cenk Erdal and Lale Cerrahoğlu},
  journal={Annals of the rheumatic diseases},
  year={1997},
  volume={56 4},
  pages={275-7}
}
OBJECTIVE This study investigated whether any genomic change occurs in DNA level in ankylosing spondylitis (AS) by measuring sister chromatid exchange (SCE) frequency. METHODS SCE frequency was detected on metaphase chromosomes obtained from peripheral blood lymphocyte cultures in 15 patients diagnosed as having AS. SCE values were also obtained from 15 healthy subjects as a control group. SCE frequencies were detected from metaphases obtained from standard blood cultures by using… CONTINUE READING

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