Sirolimus is associated with new-onset diabetes in kidney transplant recipients.

@article{Johnston2008SirolimusIA,
  title={Sirolimus is associated with new-onset diabetes in kidney transplant recipients.},
  author={Olwyn Johnston and Caren Lee Rose and Angela C Webster and John S. Gill},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2008},
  volume={19 7},
  pages={1411-8}
}
New-onset diabetes (NOD) is associated with transplant failure. A few single-center studies have suggested that sirolimus is associated with NOD, but this is not well established. With the use of data from the United States Renal Data System, this study evaluated the association between sirolimus use at the time of transplantation and NOD among 20,124 adult recipients of a first kidney transplant without diabetes. Compared with patients treated with cyclosporine and either mycophenolate mofetil… CONTINUE READING
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