Sirolimus for Retinal Astrocytic Hamartoma Associated with Tuberous Sclerosis Complex.

@article{Zhang2015SirolimusFR,
  title={Sirolimus for Retinal Astrocytic Hamartoma Associated with Tuberous Sclerosis Complex.},
  author={Zhi-qiao Zhang and Cheng Shen and Qin Long and Zhi-kun Yang and Rong-ping Dai and Jun Wang and Weihong Zhang and Qingqing Pan and Zhaohui Zhu and Kaifeng Xu},
  journal={Ophthalmology},
  year={2015},
  volume={122 9},
  pages={
          1947-9
        }
}
Mammalian target of rapamycin inhibitors for the treatment of astrocytic hamartoma in tuberous sclerosis complex (TSC)
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Regressed Retinal Astrocytic Hamartomas in Tuberous Sclerosis by Mammalian Target of Rapamycin Inhibitor (Everolimus) Treatment
Purpose: We report a case of regressed retinal astrocytic hamartomas (RAHs) in tuberous sclerosis complex (TSC) patients by mammalian target of rapamycin inhibitor (everolimus) treatment. Case
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Retinale Tumoren bilden eine heterogene Gruppe angeborener und erworbener Läsionen. Im zweiten Teil des Beitrags werden die retinozytären und Gliazelltumoren der Retina, Tumoren des retinalen
Clinical features and optical coherence tomography findings of retinal astrocytic hamartomas in Chinese patients with tuberous sclerosis complex
TLDR
A higher prevalence of TSC-associated RAH but an unexpected lower prevalence of calcified RAHs was shown in Chinese compared with that of Caucasians, suggesting SD-OCT can be used to facilitate the detection and follow-up of RAH's.
Congenital focal abnormalities of the retina and retinal pigment epithelium
TLDR
A review of the published literature on a group of developmental disorders of the retina and retinal pigment epithelium which result in focal abnormalities in one or both eyes and some are associated with other systemic abnormalities.
Glaucoma secondary to intraocular tumors: mechanisms and management
TLDR
Intraocular tumors can produce secondary glaucoma, which may involve medical therapy, transscleral cyclophotocoagulation, laser trabeculoplasty, and potentially antivascular endothelial growth factor therapy.
Retinal Astrocytic Tumors
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References

SHOWING 1-5 OF 5 REFERENCES
Ophthalmic manifestations of tuberous sclerosis: a population based study
TLDR
This is the first series to document the statistically significant association of punched out chorioretinal depigmentation with TSC and the authors believe that it should be looked for as an aid to diagnosis.
Ophthalmic Manifestations of Tuberous Sclerosis
  • D. Robertson
  • Medicine
    Annals of the New York Academy of Sciences
  • 1991
TLDR
Retinoblastoma of the optic nerve and retina is the most important lesion that must be differentiated from the hamartomas seen with tuberous sclerosis.