Sirolimus and Metformin Synergistically Inhibits Colon Cancer In Vitro and In Vivo

Abstract

We estimated the effect of various immunosuppressants (ISs) and metformin (M) to provide theoretical background of optimal therapeutic strategy for de novo colon cancer after liver transplantation (LT). Three colon cancer cell lines (HT29, SW620, and HCT116) were used in in vitro studies. HT29 was also used in BALB/c-nude mice animal models. Following… (More)
DOI: 10.3346/jkms.2017.32.9.1385

Topics

9 Figures and Tables

Slides referencing similar topics