Sir John Carew Eccles, A.C. 27 January 1903 – 2 May 1997

  title={Sir John Carew Eccles, A.C. 27 January 1903 – 2 May 1997},
  author={D. Curtis and P. Andersen},
  journal={Biographical Memoirs of Fellows of the Royal Society},
  pages={159 - 187}
  • D. Curtis, P. Andersen
  • Published 2001
  • History, Biology, Medicine
  • Biographical Memoirs of Fellows of the Royal Society
Sir John Eccles, internationally recognized for his remarkable and outstanding impact on the neurosciences for more than six decades, died on 2 May 1997 at the age of 94. He performed his research in Oxford, Sydney, Dunedin, Canberra, Chicago and Buffalo from 1927 until 1975 (73)*. His numerous scientific papers and books, arising from pioneering experimental studies of synaptic mechanisms and the organization of neurons in the mammalian central nervous system, continue to have a major… Expand
8 Citations
The academic lineage of Sir John Carew Eccles (1903–1997)
The academic lineage of Sir John Eccles is reviewed; who trained him, whom he then trained and with whom he collaborated, and the subsequent impact of his trainees and collaborators on neuroscience and other areas are reviewed. Expand
The beginning of intracellular recording in spinal neurons: Facts, reflections, and speculations
The authors' modern understanding of CNS neurophysiology directly emanates from the pioneering endeavors of the five who wrote the seminal 1951/1952 articles, and the precedents to their notable achievement are discussed. Expand
This review is restricted to contributions by 20th century laureates to the understanding of fundamental nervous system function on the cellular level, although the prize has been given to neuroscientists twice this century; Arvid Carlsson, Paul Greengard, and Eric Kandel received the award in 2000 for their discoveries related to signal transduction. Expand
Pioneers in CNS inhibition: 2. Charles Sherrington and John Eccles on inhibition in spinal and supraspinal structures
The contributions of the English neurophysiologist, Charles Scott Sherrington, and his Australian PhD trainee and collaborator, John Carew Eccles, to the concept of central inhibition in the spinal cord and brain are reviewed. Expand
One, no-one and a hundred thousand brains: J.C. Eccles, J.Z. Young and the establishment of the neurosciences (1930s-1960s).
Abstract Contemporary neurosciences have grown beyond the limits of a natural science. To its most vocal advocates, the study of the human brain can provide nothing short of the basis for a newExpand
The continuing case for the Renshaw cell
It is illustrated how mature Renshaw cell properties and connectivity arise through a combination of activity‐dependent and genetically specified mechanisms. Expand
Quantification of behavior
The purpose of this Sackler Colloquium was to examine some areas of experimentation in which mathematics is used routinely and the achievements of this field of behavioral and social sciences. Expand
The rise to dominance of genetic model organisms and the decline of curiosity-driven organismal research
This study finds that NSF grant awards have declined in association with a decrease in the proportion of grants funded for experimental, rather than genetic model organism research. Expand


Life in Sherrington's laboratory His last decade at Oxford 1925–1935
  • J. Eccles
  • Psychology
  • Trends in Neurosciences
  • 1982
This year masks the fiftieth anniversary of the Nobel Prize tor physiology or medicine awarded to Charles Scott Sherringtou and Edgar Douglas Adrian "for their discoveries regarding the function ofExpand
Brain and Conscious Experience
This book represents the proceedings of a study week at the Pontifical Academy of Science in Rome, from Sept 28 to Oct 4, 1964, which included representatives of the various neurological sciences, and of editing the volume of proceedings. Expand
Some aspects of Sherrington’s contribution to neurophysiology
  • J. Eccles
  • Sociology
  • Notes and Records of the Royal Society of London
  • 1957
Since this year we are celebrating the centenary of Sherrington’s birth, it is fitting that we should try to understand and appreciate the significance of his life. Doubtless we still live too closeExpand
From electrical to chemical transmission in the central nervous system: The closing address of the Sir Henry Dale Centennial Symposium Cambridge, 19 September 1975
  • J. Eccles
  • Sociology, Medicine
  • Notes and Records of the Royal Society of London
  • 1976
The author focuses on the story as Dale told it in his many lectures, and there are present here many of those concerned in those memorable disputations, notably of course Wilhelm Feldberg, but also Marthe Vogt, Ulf von Euler, H. O. Bacq. Expand
The Ferrier Lecture: The nature of central inhibition
  • J. Eccles
  • History
  • Proceedings of the Royal Society of London. Series B. Biological Sciences
  • 1961
I feel greatly honoured by the invitation to give the Ferrier Lecture. I attended the first Ferrier Lecture, given by Sherrington in 1929, and I learned from Sherrington to value and admire theExpand
The Purposive Brain
In this book, Granit explains the physiology of vision perception as an input system and motor control as an output system, with the goal-oriented brain mediating between. When Ragnar Granit wasExpand
The mechanism of synaptic transmission.
  • J. Eccles
  • Chemistry, Medicine
  • Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie
  • 1961
There has been a remarkable uniformity of the essential features of synaptic actions for a wide variety of junctional regions in invertebrates as well as vertebrates, and general principles of synaptic action are being established. Expand
Under the Spell of the Synapse
My scientific life began when, as a 17- to 18-year-old medical student in Melbourne, I became enthused by the brain-mind problem, in particular as it related to my own experienced self-consciousness.Expand
The synapse: from electrical to chemical transmission.
  • J. Eccles
  • Biology, Medicine
  • Annual review of neuroscience
  • 1982
The controversy as to whether synaptic transmission in the central nervous system is electrical or chemical played a key role in the origin of modern neuroscience, and I shall attempt to give it aExpand
Functional Meaning of the Patterns of Synaptic Connections in the Cerebellum
  • J. Eccles
  • Medicine
  • Perspectives in biology and medicine
  • 1965
It is generally recognized that the cerebellum provides the greatest challenge in initial efforts to discern functional meaning in neuronal patterns, because there is such a beautiful geometrical arrangement of its unique neuronal constituents. Expand