Sir Edward Mellanby (1884–1955) GBE KCB FRCP FRS: nutrition scientist and medical research mandarin

@article{Hawgood2010SirEM,
  title={Sir Edward Mellanby (1884–1955) GBE KCB FRCP FRS: nutrition scientist and medical research mandarin},
  author={B. J. Hawgood},
  journal={Journal of Medical Biography},
  year={2010},
  volume={18},
  pages={150 - 157}
}
  • B. J. Hawgood
  • Published 1 August 2010
  • Medicine
  • Journal of Medical Biography
Edward Mellanby used the experimental method to investigate medical problems. In 1918, working at King's College for Women, London, he provided conclusive evidence that rickets is a dietary deficiency disease due to lack of a fat-soluble vitamin [D]. In Sheffield he demonstrated that cereals, in an unbalanced diet, produced rickets due to the phytic acid content reducing the availability of calcium. Mellanby became Secretary of the Medical Research Council (1933–49) but continued his research… Expand
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References

SHOWING 1-10 OF 48 REFERENCES
Croonian Lecture - Nutrition in relation to bone growth and the nervous system
  • E. Mellanby
  • Biology
  • Proceedings of the Royal Society of London. Series B - Biological Sciences
  • 1944
TLDR
The main result of the earlier work was to establish the fact that rickets was due primarily to a deficiency in the diet of an antirachitic vitamin which was fat-soluble and was either vitamin A or a substance closely allied to it in properties and distribution (1919, 1921). Expand
Edward Mellanby, 1884-1955
  • H. Dale
  • Medicine
  • Biographical Memoirs of Fellows of the Royal Society
  • 1955
TLDR
Sir Edward Mellanby succeeded in maintaining a direct and personal activity in the researches which had so long provided for him, and also for his devoted wife and scientific partner, the central aim and interest of their joint working lives. Expand
Sir Hans Adolf Krebs (1900–81), pioneer of modern medicine, architect of intermediary metabolism
  • F. Leigh
  • Medicine
  • Journal of medical biography
  • 2009
TLDR
Pierre Krebs was a Nobel Laureate in 1953 and KBE in 1958 for his three great works: The Detoxification of Ammonia, The Degradation of Foods to provide Energy for Life and Gluconeogenesis. Expand
Diet and Canine Hysteria: Experimental Production
TLDR
Canine hysteria up to 1936 has been reviewed and discussed by Hewetson (1936): here, therefore, reference will be confined to some of the experimental investigations on the subject since that date. Expand
Sir Edward Mellanby, G.B.E., K.C.B., M.D., F.R.C.P., F.R.S. (1884-1955): The Man, Research Worker, and Statesman
TLDR
For nearly six years after retiring from the post of Secretary of the Medical Research Council, he continued to engage in research work and in many scientific affairs and was one of its Vice-Presidents. Expand
INSULIN AND DIABETES
TLDR
The majority of investigators concluded that a pancreatic lhormone must exist, but that it was impossible to detect its presence in pancreatic extracts because of its destruction by the trypsin aud otlher proteolytic enzymes also present in thiem. Expand
Duties of the State in Relation to the Nation's Food Supply
  • E. Mellanby
  • Medicine, Economics
  • British medical journal
  • 1927
TLDR
Early nlephrectomy, followed by heliotherapy, gave the best results, and Tuberculin was of great value in reducing residual bladder symptoms, as otherwise cases of tuberculoiis kidney would be overlooked until they had become advanced. Expand
The State and Medical Research*
At no time has the position been more favourable than to-day for appreciating Harvey's greatness as an investigator or for acknowledging the extraordinary position he holds as a leader of medicalExpand
The part played by an accessory factor in the production of experimental rickets.
TLDR
In these experiments puppies of about two months old were fed on diets which were found to produce rickets in the course of 3-4 months, and if rickets did not develop it could be assumed that it contained some anti-rachitic factor. Expand
Unusual Case of Nutritional Anaemia
TLDR
The dosage was increased to 500,000 units daily and the patient was discharged home on April 18, having been ambulant for ten days and had gained weight and looked and felt very well. Expand
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