Boronate affinity glycosyl molecularly imprinted polymer microspheres for the determination of teicoplanin using ultra-high performance liquid chromatography coupled with tandem mass spectrometry.
- Medicine, Chemistry
- Journal of chromatography. A
The glycosyl moiety of teicoplanin was selected as the template, 4-vinylphenylboronic acid and methyl methacrylate as the functional monomers, and divinylbenzene as the cross-linker to synthesis molecularly imprinted polymer microspheres via precipitation co-polymerization to permit entrapping of glycopeptide antibiotics in slightly basic environments and keeping them entrapped under neutral conditions. Expand
Historical development of bioassays
Since maintaining a number of cultures for different bioassays in the laboratory may be difficult, a set of microbiotests have been developed which are provided as kits which contain the bioindicator organisms as spores, seeds, or dormant eggs or cysts. Expand
Energy Metabolism by the Yeast Cell
Most (not all) genera and species of yeast can ferment sugars to ethanol anaerobically. This is why research on yeast fermentation has (and still does) receive extensive financial support in many… Expand
Imidazolium and benzimidazolium-containing compounds: from simple toxic salts to highly bioactive drugs.
- Chemistry, Medicine
- Organic & biomolecular chemistry
This minireview highlights the way researchers became aware of the inherent problem of the stability and bioaccumulation of imidazolium and benzimidazlium salts and how they found inspiration to exploit their toxicity by incorporating them into new highly potent drugs. Expand
Biochemical Adaptations in Pseudomonas fluorescens Exposed to Nitric Oxide, an Endogenous Antibacterial Agent