SipB-SipC Complex Is Essential for Translocon Formation

@article{Myeni2013SipBSipCCI,
  title={SipB-SipC Complex Is Essential for Translocon Formation},
  author={Sebenzile K. Myeni and Lu Wang and Daoguo Zhou},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
The delivery of effector proteins by Salmonella across the host cell membrane requires a subset of effectors secreted by the type III secretion system (TTSS) known as translocators. SipC and SipB are translocator proteins that are inserted into host membranes and presumably form a channel that translocates type III effectors into the host cell. The molecular events of how these translocators insert into the host cell membrane remain unknown. We have previously shown that the SipC C-terminal… Expand
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