Sinorhizobium meliloti dctA mutants with partial ability to transport dicarboxylic acids.

@article{Yurgel2005SinorhizobiumMD,
  title={Sinorhizobium meliloti dctA mutants with partial ability to transport dicarboxylic acids.},
  author={Svetlana N. Yurgel and Michael L. Kahn},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 3},
  pages={1161-72}
}
Sinorhizobium meliloti dctA encodes a transport protein needed for a successful nitrogen-fixing symbiosis between the bacteria and alfalfa. Using the toxicity of the DctA substrate fluoroorotic acid as a selective agent in an iterated selection procedure, four independent S. meliloti dctA mutants were isolated that retained some ability to transport dicarboxylates. Two mutations were located in a region called motif B located in a predicted transmembrane helix of the protein that has been shown… CONTINUE READING
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